Prof. Dr. med. Christian Sadik

Department of Dermatology, Allergy, and Venereology

University of Lübeck
Ratzeburger Allee 160
23562 Lübeck

Email:christian.sadik(at)uksh.de
Phone:+49 451 3101 8451
Fax:

Publikationen

1. Murthy S, Schilf P, Patzelt S, Thieme M, Becker M, Kroger L, Bremer T, Derenda-Hell A, Knebel L, Fagiani F, Ibrahim SM, Schmidt E, Zillikens D, Sadik CD. Dapsone suppresses disease in preclinical murine models of pemphigoid diseases. J Invest Dermatol 2021; DOI: 10.1016/j.jid.2021.04.009

2. Schilf P, Schmitz M, Derenda-Hell A, Thieme M, Bremer T, Väth M, Zillikens D, Sadik CD. Inhibition of glucose metabolism abrogates the effector phase of bullous pemphigoid-like epidermolysis bullosa acquisita. J Invest Dermatol 2021 DOI: 10.1016/j.jid.2021.01.014

3. Jegodzinski L, Sezin T, Loser K, Mousavi S, Zillikens D, Sadik CD. The G protein-coupled receptor (GPR) 15 counteracts antibody-mediated skin inflammation. Front Immunol 2020; 11:1858

4. Sezin T, Ferreiros N, Jennrich M, Ochirbold K, Seutter M, Attah C, Mousavi S, Zillikens D, Geisslinger G, Sadik CD. 12/15-lipoxygenase choreographs the resolution of IgG-mediated skin inflammation. J Autoimmun 2020; 115:102528

5. Sezin T, Murthy S, Attah C, Seutter M, Holtsche MM, Hammers CM, Schmidt E, Meshrkey F, Mousavi S, Zillikens D, Nunn MA, Sadik CD. Dual inhibition of complement factor 5 and leukotriene B4 synergistically suppresses murine pemphigoid disease. JCI Insight 2019; 4

6. Bezdek S, Leng L, Busch H, Mousavi S, Rades D, Dahlke M, Zillikens D, Bucala R, Sadik CD. Macrophage Migration Inhibitory Factor (MIF) drives murine psoriasiform dermatitis. Front Immunol 2018; 9:2262

7. Sezin T, Krajewski M, Wutkowski A, Mousavi S, Chakievska L, Bieber K, Ludwig RJ, Dahlke M, Rades D, Schulze FS, Schmidt E, Kalies K, Gupta Y, Schilf P, Ibrahim SM, Konig P, Schwudke D, Zillikens D, Sadik CD. The leukotriene B4 and its receptor BLT1 act as critical drivers of neutrophil recruitment in murine bullous pemphigoid-Like epidermolysis bullosa acquisita. J Invest Dermatol 2017; 137:1104-1113

8. Sadik CD, Kim ND, Iwakura Y, Luster AD. Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcgammaR signaling. Proc Natl Acad Sci U S A 2012;109:E3177-3185

9. Chou RC, Kim ND, Sadik CD, Seung E, Lan Y, Byrne MH, Haribabu B, Iwakura Y, Luster AD. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity 2010; 33:266-278

10. Sadik CD, Bachmann M, Pfeilschifter J, Muhl H. Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA. Nucl Acid Res 2009; 37:5041-5056