2026
Y.
Mehrjerdian,
R.
Atallah,
B.
Wijaya,
C.
Hammers,
S.
Gerdes, and
G.
Heine,
Case Reports: Dupilumab in difficult-to-read bullous pemphigoid at the University Hospital Schleswig-Holstein, Campus Kiel, Frontiers in Medicine , Jan. 2026.
Case Reports: Dupilumab in difficult-to-read bullous pemphigoid at the University Hospital Schleswig-Holstein, Campus Kiel, Frontiers in Medicine , Jan. 2026.
| DOI: | 10.3389/fmed.2025.1697048 |
A.
Mahdy,
Z.
Taheri,
M.
Hoivik,
A.
Franke, and
H.
ElAbd,
High throughput profiling of the B cell repertoire identifies systemic changes in the repertoir of individuals with Crohn's disease, Frontiers in Immunology , Feb. 2026.
High throughput profiling of the B cell repertoire identifies systemic changes in the repertoir of individuals with Crohn's disease, Frontiers in Immunology , Feb. 2026.
| DOI: | 10.3389/fimmu.2026.1725813 |
K.
Sinning,
M.
Eckstein,
X.
Zhao,
A.
Rosenfeldt,
S.
Hochrein, and
M.
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The Glucose Transporter GLUT3 Controls Regulatory T Cell Function, bioRxiv , Mar. 2026.
The Glucose Transporter GLUT3 Controls Regulatory T Cell Function, bioRxiv , Mar. 2026.
| DOI: | 10.64898/2026.03.26.714439 |
S.
Gonther,
M.
Thieme,
G.
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P.
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A.
Derenda-Hell,
S.
Murthy,
M.
Hirose,
M.
Vaeth, and
C.
Sadik,
Moxifloxacin Inhibits Neutrophil Responses to Immune Complexes and Ameliorates Skin Inlfammation in a Model of Pemphigoid Diseases, Federation of American Societies for Experimental Biology , Feb. 2026.
Moxifloxacin Inhibits Neutrophil Responses to Immune Complexes and Ameliorates Skin Inlfammation in a Model of Pemphigoid Diseases, Federation of American Societies for Experimental Biology , Feb. 2026.
| DOI: | 10.1096/fj.202503040RR |
A. Hutloff,
Selective Complement Inhibition in , Cellular & Molecular Immunology , Mar. 2026.
Selective Complement Inhibition in , Cellular & Molecular Immunology , Mar. 2026.
| DOI: | 10.1038/s41423-026-01400-3 |
S.
Emtenani,
T.
Lari,
C.
Kiehne,
N.
Beek,
M.
Holtsche, and
E.
Schmidt,
Selective Complement Inhibition in Anti-p200 Pemphigoid: Immune Infiltrate Profiles and Therapeutic Implications Compared to Bullous Pemphigoid, biomolecules , Jan. 2026.
Selective Complement Inhibition in Anti-p200 Pemphigoid: Immune Infiltrate Profiles and Therapeutic Implications Compared to Bullous Pemphigoid, biomolecules , Jan. 2026.
| DOI: | 10.3390/biom16020182 |
H.
ElAbd,
A.
Mahdy,
E.
Wacker,
M.
Gretsova,
D.
Ellinghaus,
A.
Dempfile, and
A.
Franke,
T cell receptor clonotypes predict human leukocyte antigen allele carriage and antigen exposure history, Communications Biology , Jan. 2026.
T cell receptor clonotypes predict human leukocyte antigen allele carriage and antigen exposure history, Communications Biology , Jan. 2026.
| DOI: | 10.1038/s42003-025-09140-2 |
S.
Klapa,
K.
Bieber,
A.
Vorobyev,
M.
Ludwig,
G.
Vollert,
S.
Arnold,
H.
Olbrich,
H.
Nording,
A.
Müller,
K.
Kridin,
J.
Schirmer,
K.
Allwördern,
A.
Staehle,
R.
Ludwig, and
P.
Lamprecht,
ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study, Frontiers in Immunology , Apr. 2026.
ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study, Frontiers in Immunology , Apr. 2026.
| DOI: | 10.3389/fimmu.2026.1794549 |
A.
Mahdy,
H.
ElAbd,
M.
Prinzensteiner,
H.
Jebens,
K.
Sivickis,
P.
Bacher,
T.
Vogl,
M.
Poyet, and
A.
Franke,
Mapping adaptive immune responses toward fungal antigens in inflammatory bowel disease using T cell repertoire sequencing and phage-immunoprecipitation sequencing, Journal of Crohns's and Colitis , Apr. 2026.
Mapping adaptive immune responses toward fungal antigens in inflammatory bowel disease using T cell repertoire sequencing and phage-immunoprecipitation sequencing, Journal of Crohns's and Colitis , Apr. 2026.
| DOI: | 10.1093/ecco-jcc/jjag015 |
2025
B.
Laffer,
M.
Ohms,
S.
Kenno,
P.
Tsui,
E.
Ehlers-Jeske,
W.
Song,
W.
Song, and
J.
Köhl,
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
| DOI: | DOI: 10.3389/fimmu.2025.1560468 |
M.
Hibino,
T.
Filosi,
L.
Carrion,
E.
Porcu,
A.
Malhotra,
K.
Lüdtke-Buzug,
S.
Ibrahim,
Y.
Yamada, and
M.
Hirose,
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
| DOI: | 10.1016/j.biopha.2025.118019 |
H.
Wu,
M.
Prados, and
M.
Vaeth,
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mar. 2025.
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mar. 2025.
| DOI: | 10.70322/immune.2025.10005 |
S.
Preuß,
K.
Bieber,
A.
Vorobyev,
A.
Recke,
E.
Moderegger,
H.
Zirpel,
E.
Gaffal,
D.
Thaci,
K.
Kridin, and
R.
Ludwig,
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mar. 2025.
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mar. 2025.
| DOI: | 10.1111/jdv.20670 |
M.
Tigges,
S.
Dräger,
I.
Piccini,
K.
Bieber,
A.
Vorobjev,
J.
Edelkamp,
M.
Bertolini, and
R.
Ludwig,
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mar. 2025.
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mar. 2025.
| DOI: | 10.3389/fimmu.2025.1537428 |
R.
Ludwig,
M.
Anson,
H.
Zirpel,
D.
Thaci,
H.
Olbrich,
K.
Bieber,
K.
Kridin,
A.
Dempfle,
P.
Curman,
S.
Zhao, and
U.
Alam,
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mar. 2025.
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mar. 2025.
| DOI: | 10.3389/fphar.2025.1516126 |
S.
Stenger,
A.
Vorobjev,
K.
Bieber,
T.
Lange,
R.
Ludwig, and
J.
Hundt,
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
| DOI: | 10.3389/fnetp.2025.1499297 |
J.
Kwon,
H.
Kawase,
K.
Mattonet,
S.
Guenther,
L.
Hahnefeld,
J.
Shamasara,
J.
Heering,
M.
Kurz,
S.
Kirchhofer,
C.
Krasel,
M.
Ulrich,
M.
Presechino,
S.
Murthy,
C.
ORlandi,
C.
Saidk,
G.
Geisslinger,
M.
Bünemann,
P.
Kolb,
S.
Offermanns, and
N.
Wettschureck,
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
| DOI: | 10.1038/s41467-025-56713-0 |
K.
Kridin,
C.
Papara,
K.
Bieber,
D.
Luca,
J.
Klein,
M.
Ludwig,
P.
Curman,
A.
Vorobyev,
A.
Dempfle, and
R.
Ludwig,
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
| DOI: | 10.3389/fpsyt.2025.1429297 |
S.
Schacht,
J.
Graffunder,
P.
Durek,
J.
Wehrenberg,
A.
Siracusa,
C.
Biese,
M.
Mashreghi,
K.
Thurley,
L.
Bauer, and
A.
Hutloff,
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
| DOI: | 10.1038/s41423-025-01285-8 |
V.
Hartmann,
S.
Guo,
S.
Rahimi,
U.
Radine,
D.
Malheiros,
A.
Salviano-Silva,
V.
Hoch,
G.
Cipolla,
V.
Calonga-Solis,
A.
Künstner,
I.
Burmester,
R.
Ludwig,
W.
Hariton,
C.
Hammers,
E.
Müller,
H.
Busch, and
J.
Hundt,
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
| DOI: | 10.1101/2025.02.10.637416 |
S.
Mousavi,
K.
Bieber,
H.
Zirpel,
A.
Vorobyev,
H.
Olbrich,
C.
Papara,
D.
Luca,
D.
Thaci,
E.
Schmidt,
G.
Riemekasten,
P.
Lamprecht,
M.
Laudes,
K.
Kridin, and
R.
Ludwig,
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
| DOI: | 10.3389/fendo.2025.1516433 |
P.
Curman,
S.
Dräger,
H.
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G.
Hernandez,
K.
Bieber,
E.
Gaffal,
K.
Kridin,
S.
Szymczak, and
R.
Ludiwg,
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , May 2025.
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , May 2025.
T.
Lari,
L.
Macias,
L.
Robrahn,
H.
Dikmen,
J.
Prüßmann,
C.
Kiehne,
S.
Engster,
I.
Weyers,
S.
Szymczak,
N.
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M.
Hoffmann,
E.
Schmidt, and
S.
Emtenani,
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
| DOI: | 10.3390/life15020218 |
L.
Bao,
C.
Guerrero-Juarez,
J.
Li,
M.
Pigors,
S.
Emtenani,
Y.
Liu,
A.
Mansini,
Y.
Wang,
A.
Ahmed,
N.
Ishii,
T.
Hashimoto,
B.
White,
S.
Green,
K.
Kunstman,
N.
Nowak,
C.
Cole,
M.
Sarkar,
J.
Gudjonsson,
M.
Virgilia,
M.
Sverdlov,
M.
McAlexander,
C.
McCrae,
C.
Nazaroff,
E.
Schmidt, and
K.
Amber,
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
| DOI: | 10.1038/s41467-025-62495-2 |
A.
Mahdy,
J.
Fuß,
S.
Franzenburg,
M.
Vollstedt,
Y.
Dolshanskaya,
Kokubun,
V.
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F.
Tran,
C.
Bang,
M.
Hoivik,
J.
Skieceviciene,
J.
Kupcinskas,
M.
Poyet,
A.
Franke, and
H.
ElAbd,
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
| DOI: | 10.1101/2025.08.05.668736 |
