2025
Sina
Kaiser,
Ina
Suhrkamp,
Jinru
He,
Charlotte
Helf,
Christian D.
Sadik,
Michael
Weichenthal, and
Guido
Heine,
Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression, Frontiers in Immunology , Okt. 2025.
Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression, Frontiers in Immunology , Okt. 2025.
| DOI: | 10.3389/fimmu.2025.1664199 |
Xiaolin
Liu,
Sabrina
Patzelt,
Yue
Ma,
Aleksa
Cepic,
Hasan-Onur
Dikmen,
Katja
Bieber,
Mathieu
Groussin,
Mathilde
Poyet,
Saleh
Ibrahim,
Enno
Schmidt, and
John F.
Baines,
Gut Microbiota Modulates and Predicts Disease Severoty in Experimental Pemphigoid Disease, bioRxiv , Okt. 2025.
Gut Microbiota Modulates and Predicts Disease Severoty in Experimental Pemphigoid Disease, bioRxiv , Okt. 2025.
| DOI: | 10.1101/2025.10.01.679837 |
Sabrina
Patzelt,
Rengin Melis
Engin,
Kossara
Drenovska,
Charlotte
Kiehne,
Christian
Probst,
Lars
Komorowski,
Swantje
Mindorf,
Maryam
Daneshpazhooh,
Soo-Chan
Kim,
Francesca
Farnetani,
Cristina
Vaschieri,
Raghavendra
Rao,
Angelo Valerio
Marzano,
Marian
Dmochowski,
Aikaterini
Patsatsi,
Dedee
Murrell,
Johannes S.
Kern,
Hilayda Karakök
Kisla,
Eli
Sprecher,
Dipankar
De,
Giovanni Di
Zenzo,
Luca
Borradori,
Hana
Jedlickova,
Xuejun
Zhu,
Enno
Schmidt, and
Stepahnie
Goletz,
Standardized indirect immunoflourescence-based detection of dermal-binding autoantibodies in pemphigoid diseases: a prospective international multicentre study, British Journal of Dermatology , Okt. 2025.
Standardized indirect immunoflourescence-based detection of dermal-binding autoantibodies in pemphigoid diseases: a prospective international multicentre study, British Journal of Dermatology , Okt. 2025.
| DOI: | 10.1093/bjd/ljaf385 |
Natalie
Gross,
Alexander
Jochimsen,
Sören
Dräger,
Thomas
Theocharis,
Andreas
Recke,
Nina
Beek,
Leon
Schmidt-Jiménez,
Steffen
Krohn,
Katja
Klausz,
Katja
Bieber,
Ralf J.
Ludwig, and
Matthias
Peipp,
CD19xCD3 bispecific T cell engager treatment induces remission in experimental pemphigoid disease, bioRxiv , Sep. 2025.
CD19xCD3 bispecific T cell engager treatment induces remission in experimental pemphigoid disease, bioRxiv , Sep. 2025.
| DOI: | 10.1101/2025.09.09.675030 |
Maren E.
Buenning,
Sri Harini
Purusothaman,
Svea
Symannek,
Philip
Curman,
Khalaf
Kridin,
Enno
Schmidt,
Katja
Bieber, and
Ralf J.
Ludwig,
Differential risks of venous thromboembolic events in pemphigus and pemphigoid diseases, Journal of the European Academy id Dermatology & Venereology , Aug. 2025.
Differential risks of venous thromboembolic events in pemphigus and pemphigoid diseases, Journal of the European Academy id Dermatology & Venereology , Aug. 2025.
| DOI: | 10.1111/jdv.70017 |
Aya
Mahdy,
Janina
Fuß,
Sören
Franzenburg,
Melanie
Vollstedt,
Yeqgenia
Dolshanskaya,
Kokubun,
Valeriia
Kriukova,
Florian
Tran,
Corinna
Bang,
Marte Lie
Hoivik,
Jurgita
Skieceviciene,
Juozas
Kupcinskas,
Mathilde
Poyet,
Andre
Franke, and
Hesham
ElAbd,
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
| DOI: | 10.1101/2025.08.05.668736 |
Henning
Olbrich,
Sophie L.
Preuß,
Khalaf
Kridin,
Gema
Hernandez,
Diamant
Thaci,
Ralf J.
Ludwig, and
Philip
Curman,
COVID-19 infection raises respiratory type-2 inflammation disease risk, whereas vaccination is protective, The Journal of Allergy and Clinical Immunology , Jul. 2025.
COVID-19 infection raises respiratory type-2 inflammation disease risk, whereas vaccination is protective, The Journal of Allergy and Clinical Immunology , Jul. 2025.
| DOI: | 10.1016/j.jaci.2025.07.030 |
Lei
Bao,
Christian F.
Guerrero-Juarez,
Jing
Li,
Manuela
Pigors,
Shirin
Emtenani,
Yingzi
Liu,
Adrian P.
Mansini,
Yulu F.
Wang,
Aadil
Ahmed,
Norito
Ishii,
Takashi
Hashimoto,
Bethany E. Perez
White,
Stefan
Green,
Kevin
Kunstman,
Nicole C.
Nowak,
Connor
Cole,
Mrinal K.
Sarkar,
Johann E.
Gudjonsson,
Macias
Virgilia,
Maria
Sverdlov,
M. Allen
McAlexander,
Christopher
McCrae,
Christopher D.
Nazaroff,
Enno
Schmidt, and
Kyle T.
Amber,
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
| DOI: | 10.1038/s41467-025-62495-2 |
Sören
Dräger,
Claudia
Kauderer,
Svenja
Meyhöfer,
Leonie
Dräger,
Jens U.
Marquardt,
Ralf J.
Ludwig,
Stephan
Arndt,
Katharina
Boch, and
Katja
Bieber,
Sita- and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross-sectional study, Journal of the European Academy of Dermatology & Venereology , Jun. 2025.
Sita- and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross-sectional study, Journal of the European Academy of Dermatology & Venereology , Jun. 2025.
| DOI: | 10.1111/jdv.20885 |
Philip
Curman,
Sören
Dräger,
Henning
Olbrich,
Gema
Hernandez,
Katja
Bieber,
Evelyn
Gaffal,
Khalaf
Kridin,
Silke
Szymczak, and
Ralf J.
Ludiwg,
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , Mai 2025.
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , Mai 2025.
Kaan
Yilmaz,
Stephanie
Goletz,
Christoph M.
Hammers,
Katharina
Boch,
Claudia
Zeidler,
Henning
Wiegmann,
Estelle
Bergmann,
Tina Rastegar
Lari,
Onur
Dikmen,
Nina
Härding,
Robert
Strohal,
Andreas
Kleinheinz,
Eva N.
Hadaschik,
Nina
Beek,
Sonja
Ständer, and
Enno
Schmidt,
Clinical and immunopathological spectrum of immunoglobulin M pemphigoid: a multicenter case series, Journal der Deutshen Dermatologischen Gesellschaft , Mai 2025.
Clinical and immunopathological spectrum of immunoglobulin M pemphigoid: a multicenter case series, Journal der Deutshen Dermatologischen Gesellschaft , Mai 2025.
| DOI: | 10.1111/ddg.15838 |
Björn
Laffer,
Mareike
Ohms,
Samyr
Kenno,
Ping
Tsui,
Elvira
Ehlers-Jeske,
Wenru
Song,
Wen-Chao
Song, and
Jörg
Köhl,
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
| DOI: | DOI: 10.3389/fimmu.2025.1560468 |
Sarah-Sophie
Schacht,
Josefine
Graffunder,
Pawel
Durek,
Jonas
Wehrenberg,
Anette
Siracusa,
Charlotte
Biese,
Mir-Farzin
Mashreghi,
Kevin
Thurley,
Laura
Bauer, and
Andreas
Hutloff,
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
| DOI: | 10.1038/s41423-025-01285-8 |
Sarah
Stenger,
Artem
Vorobjev,
Katja
Bieber,
Tanja
Lange,
Ralf J.
Ludwig, and
Jennifer E.
Hundt,
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
| DOI: | 10.3389/fnetp.2025.1499297 |
Mitsue
Hibino,
Tobia
Filosi,
Libia Lara
Carrion,
Emilio
Porcu,
Ankit
Malhotra,
Kerstin
Lüdtke-Buzug,
Saleh M.
Ibrahim,
Yuma
Yamada, and
Misa
Hirose,
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
| DOI: | 10.1016/j.biopha.2025.118019 |
Hao
Wu,
Miriam Campillo
Prados, and
Martin
Vaeth,
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mä. 2025.
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mä. 2025.
| DOI: | 10.70322/immune.2025.10005 |
Marvin
Tigges,
Sören
Dräger,
Ilaria
Piccini,
Katja
Bieber,
Artem
Vorobjev,
Janin
Edelkamp,
Marta
Bertolini, and
Ralf J.
Ludwig,
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mä. 2025.
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mä. 2025.
| DOI: | 10.3389/fimmu.2025.1537428 |
Sophie L.
Preuß,
Katja
Bieber,
Artem
Vorobyev,
Andreas
Recke,
Eva Lotta
Moderegger,
Henner
Zirpel,
Evelyn
Gaffal,
Diamant
Thaci,
Khalaf
Kridin, and
Ralf J.
Ludwig,
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mä. 2025.
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mä. 2025.
| DOI: | 10.1111/jdv.20670 |
Ralf J.
Ludwig,
Matthew
Anson,
Henner
Zirpel,
Diamant
Thaci,
Henning
Olbrich,
Katja
Bieber,
Khalaf
Kridin,
Astrid
Dempfle,
Philip
Curman,
Sizheng S.
Zhao, and
Uazman
Alam,
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mä. 2025.
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mä. 2025.
| DOI: | 10.3389/fphar.2025.1516126 |
Veronika
Hartmann,
Sen
Guo,
Siavash
Rahimi,
Uta
Radine,
Danielle
Malheiros,
Amanda
Salviano-Silva,
Valeria Bumiller-Bini
Hoch,
Gabriela A
Cipolla,
Veronica
Calonga-Solis,
Axel
Künstner,
Imke
Burmester,
Ralf J.
Ludwig,
William V.J.
Hariton,
Christoph M:
Hammers,
Eliane J.
Müller,
Hauke
Busch, and
Jennifer
Hundt,
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
| DOI: | 10.1101/2025.02.10.637416 |
Khalaf
Kridin,
Cristian
Papara,
Katja
Bieber,
David A. De
Luca,
Jan Philipp
Klein,
Marlene A.
Ludwig,
Philip
Curman,
Artem
Vorobyev,
Astrid
Dempfle, and
Ralf J.
Ludwig,
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
| DOI: | 10.3389/fpsyt.2025.1429297 |
Jeongheyeon
Kwon,
Haruya
Kawase,
Kenny
Mattonet,
Stefan
Guenther,
Lisa
Hahnefeld,
Jamal
Shamasara,
Jan
Heering,
Michael
Kurz,
Sina
Kirchhofer,
Cornelius
Krasel,
Michaela
Ulrich,
Margherita
Presechino,
Sripriya
Murthy,
Ceare
ORlandi,
Christian
Saidk,
Gerd
Geisslinger,
Moritz
Bünemann,
Peter
Kolb,
Stefan
Offermanns, and
Nina
Wettschureck,
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
| DOI: | 10.1038/s41467-025-56713-0 |
Sadegh
Mousavi,
Katja
Bieber,
Henner
Zirpel,
Artem
Vorobyev,
Henning
Olbrich,
Cristian
Papara,
David A. De
Luca,
Diamant
Thaci,
Enno
Schmidt,
Gabriele
Riemekasten,
Peter
Lamprecht,
MAtthias
Laudes,
Khalaf
Kridin, and
Ralf J.
Ludwig,
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
| DOI: | 10.3389/fendo.2025.1516433 |
Tina Rastegar
Lari,
Louis
Macias,
Lara
Robrahn,
Hasan Onur
Dikmen,
Jasper
Prüßmann,
Charlotte
Kiehne,
Simon
Engster,
Imke
Weyers,
Silke
Szymczak,
Nina
Beek,
Markus H.
Hoffmann,
Enno
Schmidt, and
Shirin
Emtenani,
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
| DOI: | 10.3390/life15020218 |
2024
Aya K.H.
Mahdy,
Valentina
Schöpfel,
Gert
Huppertz-Hauss,
Gori
Perminow,
Florian
Tran,
Corinna
Bang,
Johannes Roksund
Hov,
May-Bente
Bengtson,
Petr
Ricanek,
Randi
Opheim,
Tone Bergene
Aabrekk,
Trond Espen
Detlie,
Vendel A.
Kristensen,
Mathilde
Poyet,
MArtie Lie
Hoivik,
Andre
Franke, and
Hesham
ElAbd,
Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients, BioRxiv , Sep. 2024.
Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients, BioRxiv , Sep. 2024.
| DOI: | 10.1101/2024.09.22.614337 |
