2025

Maren E. Buenning, Sri Harini Purusothaman, Svea Symannek, Philip Curman, Khalaf Kridin, Enno Schmidt, Katja Bieber, and Ralf J. Ludwig,
Differential risks of venous thromboembolic events in pemphigus and pemphigoid diseases, Journal of the European Academy id Dermatology & Venereology , Aug. 2025.
DOI:10.1111/jdv.70017
Aya Mahdy, Janina Fuß, Sören Franzenburg, Melanie Vollstedt, Yeqgenia Dolshanskaya, Kokubun, Valeriia Kriukova, Florian Tran, Corinna Bang, Marte Lie Hoivik, Jurgita Skieceviciene, Juozas Kupcinskas, Mathilde Poyet, Andre Franke, and Hesham ElAbd,
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
DOI:10.1101/2025.08.05.668736
Henning Olbrich, Sophie L. Preuß, Khalaf Kridin, Gema Hernandez, Diamant Thaci, Ralf J. Ludwig, and Philip Curman,
COVID-19 infection raises respiratory type-2 inflammation disease risk, whereas vaccination is protective, The Journal of Allergy and Clinical Immunology , Jul. 2025.
DOI:10.1016/j.jaci.2025.07.030
Lei Bao, Christian F. Guerrero-Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Adrian P. Mansini, Yulu F. Wang, Aadil Ahmed, Norito Ishii, Takashi Hashimoto, Bethany E. Perez White, Stefan Green, Kevin Kunstman, Nicole C. Nowak, Connor Cole, Mrinal K. Sarkar, Johann E. Gudjonsson, Macias Virgilia, Maria Sverdlov, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Enno Schmidt, and Kyle T. Amber,
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
DOI:10.1038/s41467-025-62495-2
Sören Dräger, Claudia Kauderer, Svenja Meyhöfer, Leonie Dräger, Jens U. Marquardt, Ralf J. Ludwig, Stephan Arndt, Katharina Boch, and Katja Bieber,
Sita- and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross-sectional study, Journal of the European Academy of Dermatology & Venereology , Jun. 2025.
DOI:10.1111/jdv.20885
Philip Curman, Sören Dräger, Henning Olbrich, Gema Hernandez, Katja Bieber, Evelyn Gaffal, Khalaf Kridin, Silke Szymczak, and Ralf J. Ludwig,
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , Mai 2025.
DOI:10.2139/ssrn.5246532
Kaan Yilmaz, Stephanie Goletz, Christoph M. Hammers, Katharina Boch, Claudia Zeidler, Henning Wiegmann, Estelle Bergmann, Tina Rastegar Lari, Onur Dikmen, Nina Härding, Robert Strohal, Andreas Kleinheinz, Eva N. Hadaschik, Nina Beek, Sonja Ständer, and Enno Schmidt,
Clinical and immunopathological spectrum of immunoglobulin M pemphigoid: a multicenter case series, Journal der Deutshen Dermatologischen Gesellschaft , Mai 2025.
DOI:10.1111/ddg.15838
Björn Laffer, Mareike Ohms, Samyr Kenno, Ping Tsui, Elvira Ehlers-Jeske, Wenru Song, Wen-Chao Song, and Jörg Köhl,
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
DOI:DOI: 10.3389/fimmu.2025.1560468
Sarah-Sophie Schacht, Josefine Graffunder, Pawel Durek, Jonas Wehrenberg, Anette Siracusa, Charlotte Biese, Mir-Farzin Mashreghi, Kevin Thurley, Laura Bauer, and Andreas Hutloff,
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
DOI:10.1038/s41423-025-01285-8
Sarah Stenger, Artem Vorobjev, Katja Bieber, Tanja Lange, Ralf J. Ludwig, and Jennifer E. Hundt,
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
DOI:10.3389/fnetp.2025.1499297
Mitsue Hibino, Tobia Filosi, Libia Lara Carrion, Emilio Porcu, Ankit Malhotra, Kerstin Lüdtke-Buzug, Saleh M. Ibrahim, Yuma Yamada, and Misa Hirose,
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
DOI:10.1016/j.biopha.2025.118019
Hao Wu, Miriam Campillo Prados, and Martin Vaeth,
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mä. 2025.
DOI:10.70322/immune.2025.10005
Marvin Tigges, Sören Dräger, Ilaria Piccini, Katja Bieber, Artem Vorobjev, Janin Edelkamp, Marta Bertolini, and Ralf J. Ludwig,
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mä. 2025.
DOI:10.3389/fimmu.2025.1537428
Sophie L. Preuß, Katja Bieber, Artem Vorobyev, Andreas Recke, Eva Lotta Moderegger, Henner Zirpel, Evelyn Gaffal, Diamant Thaci, Khalaf Kridin, and Ralf J. Ludwig,
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mä. 2025.
DOI:10.1111/jdv.20670
Ralf J. Ludwig, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Astrid Dempfle, Philip Curman, Sizheng S. Zhao, and Uazman Alam,
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mä. 2025.
DOI:10.3389/fphar.2025.1516126
Veronika Hartmann, Sen Guo, Siavash Rahimi, Uta Radine, Danielle Malheiros, Amanda Salviano-Silva, Valeria Bumiller-Bini Hoch, Gabriela A Cipolla, Veronica Calonga-Solis, Axel Künstner, Imke Burmester, Ralf J. Ludwig, William V.J. Hariton, Christoph M: Hammers, Eliane J. Müller, Hauke Busch, and Jennifer Hundt,
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
DOI:10.1101/2025.02.10.637416
Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Artem Vorobyev, Astrid Dempfle, and Ralf J. Ludwig,
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
DOI:10.3389/fpsyt.2025.1429297
Jeongheyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamasara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Presechino, Sripriya Murthy, Ceare ORlandi, Christian Saidk, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, and Nina Wettschureck,
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
DOI:10.1038/s41467-025-56713-0
Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, MAtthias Laudes, Khalaf Kridin, and Ralf J. Ludwig,
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
DOI:10.3389/fendo.2025.1516433
Tina Rastegar Lari, Louis Macias, Lara Robrahn, Hasan Onur Dikmen, Jasper Prüßmann, Charlotte Kiehne, Simon Engster, Imke Weyers, Silke Szymczak, Nina Beek, Markus H. Hoffmann, Enno Schmidt, and Shirin Emtenani,
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
DOI:10.3390/life15020218

2024

Konstantin Stark, Badr Kilani, Sven Stockhausen, Johanna Busse, Irene Schubert, Thuy-Duong Tran, Florian Gaertner, Alexander Leuning, Kami Pekayvaz, Leo Nicolai, Valeria Fumagalli, Julia Stermann, Felix Stephan, Christian David, Martin B. M??ller, Birgitta Heyman, Anja Lux, Alexandra Guerreiro, Lukas P. Frenzel, Christoph Q. Schmidt, Arthur Dopler, Markus Moser, Sue Chandrarantne, Marie-Luise Brühl, Michael Lorenz, Thomas Korff, Martina Rudelius, Oliver Popp, Marieluise Kirchner, Philipp Mertins, Falk Nimmerjahn, Matteo Iannacone, Markus Sperandio, Berd Engelmann, Admar Verschoor, and Steffen Massberg,
Antibodies and complement are key drivers of thrombosis, Immunity , Sep. 2024.
DOI:10.1016/j.immuni.2024.08.007
Steffen Krohn, Tosca Holtrop, Arianne M. Brandsma, Petra Moerer, Maaike Nederend, Nikos Darzentas, Monika Brüggemann, Katja Klausz, JEanette H. Leusen, and Matthias Peipp,
Combining Cellular Immunization and Phage Display Screening Results in Novel, FcgammaR1-Specific Antiboides, viruses , Apr. 2024.
DOI:10.3390/v16040596
Manuela Pigors, Stephanie Goletz, Yao Wang, Shirin Emtenani, Christoph M. Hammers, Maike Holtsche, Sabrina Patzelt, Bianca Opelka, Felix H. Stang, Inke R. König, Christiane Radzimski, Lars Komorowski, Monique Aumailley, Cristia Has, and Enno Schmidt,
Anti-Laminin beta4 IgG Drives Tissue damage in Anti-p200 Pemphigoid and Shows Interaction with Laminin alpha3 and gamma1/2 Chains, Journal of Investigative Dermatology , Apr. 2024.
DOI:10.1016/j.jid.2024.08.004

2023

Ulrike Raap, Maren M. Limberg, Khalaf Kridin, and Ralf J. Ludwig,
Pruritus Is Associated with an Increased Risk for the Diagnosis of Autoimmune Skin Blistering Diseases: A Propensity-Matched Global Study, Biomolecules , Mä. 2023.
DOI:10.3390/biom13030485

2022

Swantja C. Haeger, Khalaf Kridin, Mario Pieper, Laura Griewahn, Falk Nimmerjahn, Detlef Zillikens, Peter König, Ralf J. Ludwig, and Jennifer E. Hundt,
Therapeutic effects of Fcgamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita, Frontiers in Immunology , Okt. 2022.
DOI:10.3389/fimmu.2022.938306