2026

Yasmin Mehrjerdian, Rayane Atallah, Bernard Wijaya, Christoph M. Hammers, Sascha Gerdes, and Guido Heine,
Case Reports: Dupilumab in difficult-to-read bullous pemphigoid at the University Hospital Schleswig-Holstein, Campus Kiel, Frontiers in Medicine , Jan. 2026.
DOI:10.3389/fmed.2025.1697048
Aya Mahdy, Zahara Taheri, MArete Lue Hoivik, Andre Franke, and Hesham ElAbd,
High throughput profiling of the B cell repertoire identifies systemic changes in the repertoir of individuals with Crohn's disease, Frontiers in Immunology , Feb. 2026.
DOI:10.3389/fimmu.2026.1725813
Katrin Sinning, Miriam Eckstein, Xiufeng Zhao, Alexandra Freitag MAthias Rosenfeldt, Sophia M. Hochrein, and Martin Vaeth,
The Glucose Transporter GLUT3 Controls Regulatory T Cell Function, bioRxiv , Mä. 2026.
DOI:10.64898/2026.03.26.714439
Sina Gonther, Markus Thieme, Gabriela F. Gubert, Paul Schilf, Aleksandra Derenda-Hell, Sripriya Murthy, Misa Hirose, Martin Vaeth, and Christian D. Sadik,
Moxifloxacin Inhibits Neutrophil Responses to Immune Complexes and Ameliorates Skin Inlfammation in a Model of Pemphigoid Diseases, Federation of American Societies for Experimental Biology , Feb. 2026.
DOI:10.1096/fj.202503040RR
Andreas Hutloff,
Selective Complement Inhibition in , Cellular & Molecular Immunology , Mä. 2026.
DOI:10.1038/s41423-026-01400-3
Shirin Emtenani, Tina Rastegar Lari, Charlotte Kiehne, Nina Beek, Maike M. Holtsche, and Enno Schmidt,
Selective Complement Inhibition in Anti-p200 Pemphigoid: Immune Infiltrate Profiles and Therapeutic Implications Compared to Bullous Pemphigoid, biomolecules , Jan. 2026.
DOI:10.3390/biom16020182
Hesham ElAbd, Aya H. Mahdy, Eike Matthias Wacker, Maria Gretsova, David Ellinghaus, Astrid Dempfile, and Andre Franke,
T cell receptor clonotypes predict human leukocyte antigen allele carriage and antigen exposure history, Communications Biology , Jan. 2026.
DOI:10.1038/s42003-025-09140-2
Sebastian Klapa, Katja Bieber, Artem Vorobyev, Marlene Ludwig, Gordon Vollert, Sabrina Arnold, Henning Olbrich, Henry Nording, Antje Müller, Khalaf Kridin, Jan Henrik Schirmer, Katja Allwördern, Anja Staehle, Ralf Ludwig, and Peter Lamprecht,
ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study, Frontiers in Immunology , Apr. 2026.
DOI:10.3389/fimmu.2026.1794549
Aya H. Mahdy, Hesham ElAbd, Melanie Prinzensteiner, Hannah Jebens, Kostas Sivickis, Petra Bacher, Thomas Vogl, Mathilde Poyet, and Andre Franke,
Mapping adaptive immune responses toward fungal antigens in inflammatory bowel disease using T cell repertoire sequencing and phage-immunoprecipitation sequencing, Journal of Crohns's and Colitis , Apr. 2026.
DOI:10.1093/ecco-jcc/jjag015

2025

Björn Laffer, Mareike Ohms, Samyr Kenno, Ping Tsui, Elvira Ehlers-Jeske, Wenru Song, Wen-Chao Song, and Jörg Köhl,
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoiummune blistering dermatosis, Frontiers in Immunology , Apr. 2025.
DOI:DOI: 10.3389/fimmu.2025.1560468
Mitsue Hibino, Tobia Filosi, Libia Lara Carrion, Emilio Porcu, Ankit Malhotra, Kerstin Lüdtke-Buzug, Saleh M. Ibrahim, Yuma Yamada, and Misa Hirose,
An effective approach to modulate mitochondrial function in murine primary macrophages by a mitochondria-targeted nanocapsule, MITO-Porter, Biomedicine & Pharmacotherapy , Apr. 2025.
DOI:10.1016/j.biopha.2025.118019
Hao Wu, Miriam Campillo Prados, and Martin Vaeth,
Metabolic Regulation of T Cell Exhaustion, Immune Discovery , Mä. 2025.
DOI:10.70322/immune.2025.10005
Sophie L. Preuß, Katja Bieber, Artem Vorobyev, Andreas Recke, Eva Lotta Moderegger, Henner Zirpel, Evelyn Gaffal, Diamant Thaci, Khalaf Kridin, and Ralf J. Ludwig,
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mä. 2025.
DOI:10.1111/jdv.20670
Marvin Tigges, Sören Dräger, Ilaria Piccini, Katja Bieber, Artem Vorobjev, Janin Edelkamp, Marta Bertolini, and Ralf J. Ludwig,
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mä. 2025.
DOI:10.3389/fimmu.2025.1537428
Ralf J. Ludwig, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Astrid Dempfle, Philip Curman, Sizheng S. Zhao, and Uazman Alam,
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mä. 2025.
DOI:10.3389/fphar.2025.1516126
Sarah Stenger, Artem Vorobjev, Katja Bieber, Tanja Lange, Ralf J. Ludwig, and Jennifer E. Hundt,
Insomnia increases the risk for specific autoimmune diseases: a large-scale retroperspective cohort study, Frontiers in Network Physiology , Apr. 2025.
DOI:10.3389/fnetp.2025.1499297
Jeongheyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamasara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Presechino, Sripriya Murthy, Ceare ORlandi, Christian Saidk, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, and Nina Wettschureck,
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
DOI:10.1038/s41467-025-56713-0
Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Artem Vorobyev, Astrid Dempfle, and Ralf J. Ludwig,
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
DOI:10.3389/fpsyt.2025.1429297
Sarah-Sophie Schacht, Josefine Graffunder, Pawel Durek, Jonas Wehrenberg, Anette Siracusa, Charlotte Biese, Mir-Farzin Mashreghi, Kevin Thurley, Laura Bauer, and Andreas Hutloff,
Activation and maturation of antigen-specific B cells in nonectopic lung infiltrates are independent of germinal center reactions in the draining lymph node, Cellular & Molecular Immunology , Apr. 2025.
DOI:10.1038/s41423-025-01285-8
Veronika Hartmann, Sen Guo, Siavash Rahimi, Uta Radine, Danielle Malheiros, Amanda Salviano-Silva, Valeria Bumiller-Bini Hoch, Gabriela A Cipolla, Veronica Calonga-Solis, Axel Künstner, Imke Burmester, Ralf J. Ludwig, William V.J. Hariton, Christoph M: Hammers, Eliane J. Müller, Hauke Busch, and Jennifer Hundt,
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
DOI:10.1101/2025.02.10.637416
Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, MAtthias Laudes, Khalaf Kridin, and Ralf J. Ludwig,
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
DOI:10.3389/fendo.2025.1516433
Philip Curman, Sören Dräger, Henning Olbrich, Gema Hernandez, Katja Bieber, Evelyn Gaffal, Khalaf Kridin, Silke Szymczak, and Ralf J. Ludiwg,
Identifying common risk factors for primary cellulitis in a large-scale retrospective cohort study, Preprints with THE LANCET , Mai 2025.
Tina Rastegar Lari, Louis Macias, Lara Robrahn, Hasan Onur Dikmen, Jasper Prüßmann, Charlotte Kiehne, Simon Engster, Imke Weyers, Silke Szymczak, Nina Beek, Markus H. Hoffmann, Enno Schmidt, and Shirin Emtenani,
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
DOI:10.3390/life15020218
Lei Bao, Christian F. Guerrero-Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Adrian P. Mansini, Yulu F. Wang, Aadil Ahmed, Norito Ishii, Takashi Hashimoto, Bethany E. Perez White, Stefan Green, Kevin Kunstman, Nicole C. Nowak, Connor Cole, Mrinal K. Sarkar, Johann E. Gudjonsson, Macias Virgilia, Maria Sverdlov, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Enno Schmidt, and Kyle T. Amber,
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent proinflammatory response in keratinocytes, nature communications , Jul. 2025.
DOI:10.1038/s41467-025-62495-2
Aya Mahdy, Janina Fuß, Sören Franzenburg, Melanie Vollstedt, Yeqgenia Dolshanskaya, Kokubun, Valeriia Kriukova, Florian Tran, Corinna Bang, Marte Lie Hoivik, Jurgita Skieceviciene, Juozas Kupcinskas, Mathilde Poyet, Andre Franke, and Hesham ElAbd,
Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire, bioRxiv , Aug. 2025.
DOI:10.1101/2025.08.05.668736