2025

Marvin Tigges, Sören Dräger, Ilaria Piccini, Katja Bieber, Artem Vorobjev, Janin Edelkamp, Marta Bertolini, and Ralf J. Ludwig,
Pemphigoid disease model systems for clinical translation, Frontiers in Immunology , Mä. 2025.
DOI:10.3389/fimmu.2025.1537428
Sophie L. Preuß, Katja Bieber, Artem Vorobyev, Andreas Recke, Eva Lotta Moderegger, Henner Zirpel, Evelyn Gaffal, Diamant Thaci, Khalaf Kridin, and Ralf J. Ludwig,
Dupilumab shows no elevated risk for maternal adverse pregnancy outcomes: A propensity-matched cohort study, Journal of the European Academy of Dermatology & Venereology , Mä. 2025.
DOI:10.1111/jdv.20670
Ralf J. Ludwig, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Astrid Dempfle, Philip Curman, Sizheng S. Zhao, and Uazman Alam,
A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX, Frontiers in Pharmacology , Mä. 2025.
DOI:10.3389/fphar.2025.1516126
Veronika Hartmann, Sen Guo, Siavash Rahimi, Uta Radine, Danielle Malheiros, Amanda Salviano-Silva, Valeria Bumiller-Bini Hoch, Gabriela A Cipolla, Veronica Calonga-Solis, Axel Künstner, Imke Burmester, Ralf J. Ludwig, William V.J. Hariton, Christoph M: Hammers, Eliane J. Müller, Hauke Busch, and Jennifer Hundt,
In pemphigus, cell detachment, but not autoantibody binding, induces cell-wide, long lasting transcriptomic and proteomic changes, bioRxiv , Feb. 2025.
DOI:10.1101/2025.02.10.637416
Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Artem Vorobyev, Astrid Dempfle, and Ralf J. Ludwig,
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retroperspective cohort study, Frontoers in Psychiatry , Feb. 2025.
DOI:10.3389/fpsyt.2025.1429297
Jeongheyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamasara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Presechino, Sripriya Murthy, Ceare ORlandi, Christian Saidk, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, and Nina Wettschureck,
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling, nature communications , Feb. 2025.
DOI:10.1038/s41467-025-56713-0
Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, MAtthias Laudes, Khalaf Kridin, and Ralf J. Ludwig,
Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatroy diseases, Frontiers in Endocrinology , Feb. 2025.
DOI:10.3389/fendo.2025.1516433
Tina Rastegar Lari, Louis Macias, Lara Robrahn, Hasan Onur Dikmen, Jasper Prüßmann, Charlotte Kiehne, Simon Engster, Imke Weyers, Silke Szymczak, Nina Beek, Markus H. Hoffmann, Enno Schmidt, and Shirin Emtenani,
Localization of Lesions in Autoimmune Blistering Diseases Is Independent of Site-Speicific Target Antigen Expression, Life , Jan. 2025.
DOI:10.3390/life15020218

2024

Aya K.H. Mahdy, Valentina Schöpfel, Gert Huppertz-Hauss, Gori Perminow, Florian Tran, Corinna Bang, Johannes Roksund Hov, May-Bente Bengtson, Petr Ricanek, Randi Opheim, Tone Bergene Aabrekk, Trond Espen Detlie, Vendel A. Kristensen, Mathilde Poyet, MArtie Lie Hoivik, Andre Franke, and Hesham ElAbd,
Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients, BioRxiv , Sep. 2024.
DOI:10.1101/2024.09.22.614337
Konstantin Stark, Badr Kilani, Sven Stockhausen, Johanna Busse, Irene Schubert, Thuy-Duong Tran, Florian Gaertner, Alexander Leuning, Kami Pekayvaz, Leo Nicolai, Valeria Fumagalli, Julia Stermann, Felix Stephan, Christian David, Martin B. M??ller, Birgitta Heyman, Anja Lux, Alexandra Guerreiro, Lukas P. Frenzel, Christoph Q. Schmidt, Arthur Dopler, Markus Moser, Sue Chandrarantne, Marie-Luise Brühl, Michael Lorenz, Thomas Korff, Martina Rudelius, Oliver Popp, Marieluise Kirchner, Philipp Mertins, Falk Nimmerjahn, Matteo Iannacone, Markus Sperandio, Berd Engelmann, Admar Verschoor, and Steffen Massberg,
Antibodies and complement are key drivers of thrombosis, Immunity , Sep. 2024.
DOI:10.1016/j.immuni.2024.08.007
Shirin Emtenani, Hélène Lebhar, Christopher P. Marquis, Ralf J. Ludwig, and Enno Schmidt,
Granzyme B inhibition reduces autoantibody-induced dermal-epidermal separation in an ex vivo model of epidermolysis bullosa acquisita, Experimental Dermatology , Aug. 2024.
DOI:10.1111/exd.15172
Aya K.H. Mahdy, Zahra Taheri, Marte Lie Hoivik, Andre Franke, and Hesham ElAbd,
High throughput profiling of the B cell repertoire identifies systemic changes in the repertoire of individuals with Crohn's disease, bioRxiv , Aug. 2024.
DOI:10.1111/exd.15172
Steffen Krohn, Tosca Holtrop, Arianne M. Brandsma, Petra Moerer, Maaike Nederend, Nikos Darzentas, Monika Brüggemann, Katja Klausz, JEanette H. Leusen, and Matthias Peipp,
Combining Cellular Immunization and Phage Display Screening Results in Novel, FcgammaR1-Specific Antiboides, viruses , Apr. 2024.
DOI:10.3390/v16040596
Manuela Pigors, Stephanie Goletz, Yao Wang, Shirin Emtenani, Christoph M. Hammers, Maike Holtsche, Sabrina Patzelt, Bianca Opelka, Felix H. Stang, Inke R. König, Christiane Radzimski, Lars Komorowski, Monique Aumailley, Cristia Has, and Enno Schmidt,
Anti-Laminin beta4 IgG Drives Tissue damage in Anti-p200 Pemphigoid and Shows Interaction with Laminin alpha3 and gamma1/2 Chains, Journal of Investigative Dermatology , Apr. 2024.
DOI:10.1016/j.jid.2024.08.004

2023

Ulrike Raap, Maren M. Limberg, Khalaf Kridin, and Ralf J. Ludwig,
Pruritus Is Associated with an Increased Risk for the Diagnosis of Autoimmune Skin Blistering Diseases: A Propensity-Matched Global Study, Biomolecules , Mä. 2023.
DOI:10.3390/biom13030485

2022

Swantja C. Haeger, Khalaf Kridin, Mario Pieper, Laura Griewahn, Falk Nimmerjahn, Detlef Zillikens, Peter König, Ralf J. Ludwig, and Jennifer E. Hundt,
Therapeutic effects of Fcgamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita, Frontiers in Immunology , Okt. 2022.
DOI:10.3389/fimmu.2022.938306
Jovan Schanzenbacher, Joerg Koehl, and Christian M. Karsten,
Anaphylatoxins spark the flame in early autoimmunity, Frontiers in Immunology , Jul. 2022.
DOI:10.3389/fimmu.2022.958392
Ondrej Suchanek, John R. Ferdinand, Zewen K. Tuong, Sathi Wijeyesinghe, Anita Chandra, Ann-Katrin Clauder, Larissa N. Almeida, Simon Clare, Katherine Harcourt, Christopher J. Ward, Rachael Bashford-Rogers, Trevor Lawley, Rudolf A. Manz, Klaus Okkenhaug, David Masopust, and Menna R Clatworthy,
Tissue-resident B cells orchestrate macrophages polarisation and function, nature communications , Jun. 2022.
DOI:10.1038/s41467-023-42625-4