Prof. Dr. rer. nat. Andreas Hutloff

Institute of Immunology and Institute of Clinical Molecular Biology

Christian-Albrechts-University of Kiel
Arnold-Heller-Straße 3
24105 Kiel

Email:andreas.hutloff(at)uksh.de
Phone:+49 431 500 31035
Fax:

Publications

1. Scholz J, Kuhrau J, Heinrich F, Heinz GA, Hutloff A*, Worm M*, Heine G*. Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation. Allergy 2021; 76:1109

2. Lahmann A, Kuhrau J, Fuhrmann F, Heinrich F, Bauer L, Durek P, Mashreghi MF, Hutloff A. Bach2 Controls T Follicular Helper Cells by Direct Repression of Bcl-6. J Immunol 2019; 202:2229

3. Ugolini M, Gerhard J, Burkert S, Jensen KJ, Volkers S, Ebner F, Georg P, Thada S, Dietert K, Bauer L, Schäfer A, Helbig ET, Opitz B, Kurth F, Sur S, Dittrich N, Gaddam S, J. Blander M, Benn CS, Blohm U, Gruber AD, Hutloff A, Hartmann S, Boekschoten M, Müller M, Jungersen G, Schumann RR, SuttorpN, Sander LE. Recognition of microbial viability via TLR8 promotes T follicular helper cell differentiation and vaccine responses. Nat Immunol 2018; 19:386

4. Vu Van D, Beier KC, Pietzke LJ, Al Baz MS, Feist RK, Gurka S, Hamelmann E, Kroczek RA, Hutloff A. Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells. Nat Commun 2016; 7:10875

5. Paclik D, Stehle C, Lahmann A, Hutloff A*, Romagnani C*. ICOS regulates the pool of group 2 innate lymphoid cells under homeostatic and inflammatory conditions in mice. Eur J Immunol 2015; 45:2766

6. Weber JP, Fuhrmann F, Feist RK, Lahmann A, Al Baz MS, Gentz LJ, Vu Van D, Mages HW, Haftmann C, Riedel R, Grün JR, Schuh W, Kroczek RA, Radbruch A, Mashreghi MF, Hutloff A. ICOS maintains the T follicular helper cell phenotype by downregulating Krüppel-like factor 2. J Exp Med 2015; 212:217

7. Weber JP, Fuhrmann F, Hutloff A. Frontline: T follicular helper cells survive as long-term memory cells. Eur J Immunol 2012; 42:1981

8. Hutloff A, Büchner K, Reiter R, Baelde HJ, Odendahl M, Jacobi A, Dörner T, Kroczek RA. Involvement of Inducible Co-stimulator in the exaggerated memory B-cell and plasma cell generation in Systemic Lupus Erythematosus. Arthr Rheum 2004; 50:3211

9. Grimbacher B*, Hutloff A*, Schlesier M, Glocker E, Warnatz K, Dräger R, Eibel H, Fischer B, Schaffer AA, Mages HW, Kroczek RA*, Peter HH*. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol 2003; 4:261

10. Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Kraft R, Anagnostopoulos I, Kroczek RA. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999; 397:263

* equal contribution