Prof. Dr. med. Ralf Ludwig

1. Hiroyasu S, Zeglinski MR, Zhao H, Pawluk MA, Turner CT, Kasprick A, Tateishi C, Nishie W, Burleigh A, Lennox PA, Van Laeken N, Carr NJ, Petersen F, Crawford RI, Shimizu H, Tsuruta D, Ludwig RJ, Granville DJ. Granzyme B inhibition reduces disease severity in autoimmune blistering diseases. Nat Commun 2021; 12:302

2. Kasprick A, Hofrichter M, Smith B, Ward P, Bieber K, Shock A, Ludwig RJ*, Schmidt E*. Antineonatal Fc receptor (FcRn) antibody treatment ameliorates experimental epidermolysis bullosa acquisita in mice. Br J Pharmacol 2020; 177:2381

3. Vorobyev A, Gupta Y, Sezin T, Koga H, Bartsch Y, Belheouane M, Künzel S, Sina C, Schilf P, Körber-Ahrens H, Beltsiou F, Ernst A, Khilchenko S, Al-Aasam H, Manz R, Diehl S, Steinhaus M, Jascholt J, Kouki P, Boehncke W, Mayadas T, Zillikens D, Sadik C, Nishi H, Ehlers M, Möller S, Bieber K, Baines J, Ibrahim S, Ludwig RJ. Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line. Nat Commun 2019; 10:4097

4. Häberle S, Wei X, Bieber K, Goletz S, Ludwig RJ, Schmidt E, Enk AH, Hadaschik EN. Treg deficiency leads to pathogenic BP230 autoantibody and autoimmune bullous disease. J Allergy Clin Immun 2018; 142:1831-1842

5. Ludwig RJ, Vanhoorelbeke K, Leypoldt F, Kaya K, Bieber K, McLachlan SM, Komorowski L, Luo J, Cabral-Marques O, Hammers CM, Lindstrom JM, Lamprecht P, Fischer A, Riemekasten G, Tersteeg C, Sondermann P, Rapoport B, Wandinger K-P, Probst C, El Beidaq A, Schmidt E, Verkman A, Manz RA, Nimmerjahn F. Mechanisms of autoantibody-induced pathology. Front Immunol 2017; 8:603

6. Kulkarni U, Karsten CM, Tiburzy B, Meng L, Thieme L, Recke A, Pollok K, Boettcher M, Kalies K, Bogen B, Ludwig RJ, Kamradt T, Hauser AE, Langer C, Huber-Lang M, Finkelman F, Köhl J, Wong D, Manz RM. IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration. J Allergy Clin Immun 2016; 137:1487-97

7. Schindewolf M, Gobst C, Kroll H, Recke A, Louwen F, Wolter M, Kaufmann R, Boehncke WH, Lindhoff-Last E, Ludwig RJ. High incidence of heparin-induced allergic delayed-type hypersensitivity reactions in pregnancy. J Allergy Clin Immun 2013; 132:131-9

8. Karsten CM, Pandey MK, Figge J, Kilchenstein R, Taylor PR, Rosas M, McDonald JU, Orr SJ, Berger M, Petzold D, Blanchard V, Winkler A, Hess C, Reid DM, Majoul IV, Strait RT, Harris NL, Köhl G, Wex E, Ludwig RJ, Zillikens D, Nimmerjahn F, Finkelman FD, Brown GD, Ehlers M, Köhl J. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. Nat Med 2012; 18:1401-6

9. Kasperkiewicz M, Müller R, Manz R, Magens M, Hammers CM, Somlai C, Westermann J, Schmidt E, Zillikens D, Ludwig RJ*, Orosz A*. Heat shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that non-malignant plasma cells are not therapeutic targets. Blood 2011; 117:6135-42

10. Schön MP, Krahn T, Schon M, Rodriguez ML, Antonicek H, Schultz JE, Ludwig RJ, Zollner TM, Bischoff E, Bremm KD, Schramm M, Henninger K, Kaufmann R, Gollnick HP, Parker CM, Boehncke WH. Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation. Nat Med 2002; 8:366-72